The Comprehensive Metabolic Panel (CMP) is a blood test that provides information about a person’s metabolic health, offering insight into organ function, electrolyte balance, blood sugar, and protein levels. It is often ordered as part of a routine physical exam or to monitor chronic conditions and treatments.

Components of the CMP

The CMP generally includes 14 individual tests, which can be grouped as follows:

  1. Electrolytes and Fluid Balance:
    • Sodium: Helps regulate fluid balance and is essential for nerve and muscle function.
    • Potassium: Critical for heart and muscle function.
    • Chloride: Works with other electrolytes to regulate blood pressure and fluid balance.
    • Carbon dioxide (Bicarbonate): Maintains the body’s acid-base (pH) balance.
  2. Kidney Function:
    • Blood Urea Nitrogen (BUN): Waste product filtered by the kidneys; high levels may indicate kidney dysfunction.
    • Creatinine: Waste product of muscle metabolism; elevated levels suggest kidney issues.
  3. Blood Sugar (Glucose):
    • Glucose: Primary source of energy; high or low levels may indicate diabetes or other metabolic disorders.
  4. Proteins:
    • Albumin: Major protein made by the liver, crucial for maintaining fluid balance.
    • Total Protein: Measures the overall level of protein in the blood, including albumin and other proteins that help fight infection.
  5. Liver Function:
    • Alanine Aminotransferase (ALT): Enzyme found in the liver; high levels indicate liver damage.
    • Aspartate Aminotransferase (AST): Enzyme in the liver and muscles; elevated levels suggest liver or muscle damage.
    • Alkaline Phosphatase (ALP): Enzyme related to bile ducts; high levels may indicate liver or bone disease.
    • Bilirubin: Waste product from the breakdown of red blood cells; elevated levels may suggest liver or bile duct issues.

Why is the CMP Important?

The CMP is valuable for diagnosing and managing various conditions, such as:

Preparing for the CMP

Fasting for 8–12 hours before the test is often recommended to avoid affecting glucose levels.

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